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Flavopiridol pharmacokinetics. Plasma flavopiridol (A) and flavopiridol glucuronide (flavo-G, B) concentration-time profiles through 80 hours for cycle 1 in 23 of 24 patients with evaluable PK profiles (PK data from one patient extends through 150 hours due to dosing delays resulting from toxicity). Flavopiridol glucuronide concentrations were not determined for day 2.
