FIG. 3.

Effect of anti-HIV drugs on RTI-resistant isolates. C8166-R5 cells were infected with viruses having known sensitivity and resistance to RTI drugs. A total of 400 infected cells were mixed with 10⁴ uninfected C8166-R5 and cultured in the presence of the indicated drug at 5-fold dilutions. Supernatant was collected for p24 ELISA. Results are expressed as the percent inhibition compared to cultures in the absence of drug. Viruses A018 and A012 post-AZT have been defined as AZT resistant (the pre-AZT isolates are sensitive) and 1495-2 has been described as having intermediate resistance to AZT.