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. Author manuscript; available in PMC: 2011 Jun 22.
Published in final edited form as: Biochemistry. 2010 Jun 22;49(24):5048–5056. doi: 10.1021/bi1005046

Figure 5.

Figure 5

Bijvoet difference Fourier maps (contoured at 3σ) of K+ ions bound in the two monovalent cation binding sites in the D101L Fe2+-HDAC8-M344 complex. (a) Monovalent cation binding site adjacent to the active site. Metal ligands are color-coded as follows: carbon (yellow), oxygen (red), nitrogen (blue). (b). Distal monovalent cation binding site. Atoms are color-coded as in (a), and water molecules are represented as red spheres.