. Author manuscript; available in PMC: 2011 Jun 1.

Published in final edited form as: Calcif Tissue Int. 2010 Apr 20;86(6):470–483. doi: 10.1007/s00223-010-9359-y

Table 7.

Femoral neck morphology, density and mechanical properties

	Female					Male
	2 mo. (n = 11)	4 mo. (n = 11)	7 mo. (n = 10)	12 mo. (n = 10)	20 mo. (n = 8)	2 mo. (n = 11)	4 mo. (n = 10)	7 mo. (n = 11)	12 mo. (n = 9)	20 mo. (n = 11)
Bone Area^A,^S,^A-S (mm²)	0.466 ± 0.065	0.566^a ± 0.038	0.606^a ± 0.055	0.609^a ± 0.080	0.635^a ± 0.177	0.489 ± 0.048	0.564^a ± 0.065	0.604^a ± 0.076	0.511^*,^c ± 0.042	0.527^c ± 0.054
Total Area^A (mm²)	0.546 ± 0.051	0.607 ± 0.051	0.657^a ± 0.078	0.640 ± 0.088	0.739^a,^b ± 0.240	0.619 ± 0.066	0.641 ± 0.094	0.718^a,^b ± 0.096	0.615^c ± 0.064	0.690^a,^d ± 0.059
TMD^A,^S (mg HA/cm³)	1111 ± 38	1236^a ± 32	1234^a ± 31	1262^a ± 22	1235^a ± 64	1073^* ± 34	1194^*,^a ± 11	1196^*,^a ± 30	1220^*,^a ± 33	1221^a,^b,^c ± 31
Stiffness (N/mm)	28.9 ± 6.6	17.8 ± 7.9	30.8 ± 14.7	28.9 ± 9.7	31.2 ± 13.0	24.1 ± 7.7	27.7 ± 9.3	33.2 ± 11.5	28.9 ± 9.7	32.0 ± 7.1
Yield Force^A,^A-S (N)	8.2 ± 0.58	6.5 ± 2.22	10.7^a,^b ± 1.99	10.8^a,^b ± 1.42	9.9^b ± 2.40	8.1 ± 0.78	8.8 ± 2.58	9.4 ± 2.04	9.5 ± 1.90	7.6^*,^c,^d ± 2.14
Ultimate Force^A,^S,^A-S (N)	9.4 ± 0.51	9.5 ± 1.59	11.9^a,^b ± 1.94	11.7^a,^b ± 1.43	11.3^a,^b ± 1.47	8.9 ± 1.07	10.5^a ± 1.25	10.9^a ± 1.52	10.9^a ± 1.69	9.0^*,^b,^c,^d ± 1.20
Post-Yield Displ.^A (mm)	0.093 ± .0.48	0.417^a ± 0.394	0.092^b ± 0.101	0.190^b ± 0.450	0.055^b ± 0.089	0.051 ± 0.098	0.344^a ± 0.600	0.120^b ± 0.135	0.103^b ± 0.112	0.093^b ± 0.145
Energy-to-fracture^A,^S (Nmm)	2.05 ± 0.55	5.18^a ± 3.30	3.37 ± 1.17	3.20 ± 1.58	2.45^b ± 0.81	1.98 ± 0.48	3.25^a ± 1.53	2.70 ± 1.36	2.68 ± 1.29	1.71^b,^c ± 0.69

Morphology and tissue mineral density (TMD) determined by microCT at the center of the femoral neck; TMD is based on average density of the bone volume (BV); mechanical properties determined by transverse loading applied to femoral head

Significant effect of age;

Significant effect of sex;

^A-S

Significant age-sex interaction; ANOVA, p < 0.05

Male different from female at same age, p < 0.05 post hoc test

different from 2 mo;

different from 4 mo;

different from 7 mo;

different from 12 mo;

p < 0.05 post hoc test