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. Author manuscript; available in PMC: 2010 Jul 1.
Published in final edited form as: Comp Biochem Physiol C Toxicol Pharmacol. 2008 Dec 13;149(2):175–181. doi: 10.1016/j.cbpc.2008.12.002

Figure 1.

Figure 1

Estimated number of animals required in each group to provide 50% power to demonstrate a statistically significant difference (p-value of 0.1) for one excess tumor in 1000 animals based on background tumor incidence. Calculations were performed according to LaMorte WW: Sample size calculations in research. Boston University Medical Center (http://www.uml.edu/ora/institutionalcompliance/IACUC/LaMorte%20Sample%20Size%20Calc%20Paper.pdf).