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Bacterial burden in lungs and spleens of guinea pigs immunized with single doses of the different formulations after challenge with MTB H37Rv (BCG = BCG solution; PLGA ctl = blank microparticles; P-rAg85B = microparticles containing rAg85B; P-rAg85B-TDB = microparticles containing rAg85B and adjuvant TDB (average ± SD, n = 6)
