Table II.
List of Peptides That Are Detected at Significantly Different Intensities in Samples of mPFC from Rats Acutely Treated with 10 mg/kg Cocaine
| HCRs + LCRs | LCRs | ||||
|---|---|---|---|---|---|
| n = 8 | n = 4 | ||||
| Peptide | P, t test | Ratio a | Peptide | P, t test | Ratio a |
| 2168 | 0.02 | 1.7 | 2482 | 0.07 | 2 |
| 2482 | 0.02 | 2 | |||
| 2198 ATP synthase | 0.04 | 1.7 | 2198 ATP synthase | 0.07 | 1.7 |
| 2969 | 0.04 | 1.7 | |||
| 2349 Stathmin | 0.04 | 1.4 | 2349 Stathmin | 0.07 | 1.7 |
| 3480 Hint1 | 0.04 | 2 | 3480 Hint1 | 0.07 | 2.5 |
| 3434 | 0.05 | 2 | |||
Peptide masses are from the mean spectrum obtained from individual measurements, with the individual spectra being processed as described in the supplemental information
aRatio indicates relative change in peptide signal intensity in the mPFC of cocaine-treated rats, calculated as mean peak intensity in the cocaine-treated group/mean peak intensity in the control group. Peptides in bold were identified by nanoLC-FT-MS/MS