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. Author manuscript; available in PMC: 2010 Sep 17.
Published in final edited form as: Cell Host Microbe. 2009 Sep 17;6(3):279–289. doi: 10.1016/j.chom.2009.08.003

Figure 4. Identification of environmental and microbial factors that determine the fitness landscape for B. thetaiotaomicron.

Figure 4

(A) Shifts in the population structure of the ~35,000-strain B. thetaiotaomicron mutant population reflect alterations in the selective pressures on its genome. The relative abundance of each mutant in the B. thetaiotaomicron population was evaluated in multiple host genotypes (wild-type C57Bl/6; Rag1−/−; Myd88−/−) and microbial contexts. (B) qPCR assays of cecal microbial community composition in gnotobiotic mice at the time of sacrifice. The ~35,000-strain B. thetaiotamicron population is indicated with arrows.