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. 2010 Jun 7;10:11. doi: 10.1186/1471-2342-10-11

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Copyright ©2010 Murthy et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Color fundus photograph, FAF imaging, B-scan ultrasound and Spectralis OCT of subject 1. Color fundus photograph revealed yellow white surface calcareous deposits on the optic nerve head (A). FAF imaging of the same subject demonstrated autofluorescence of the surface drusen (B). B-Scan ultrasound showed echodense lesion overlapping the optic nerve shadow. The reflectivity persisted at 30 decibels (C). Cross-sectional Spectralis OCT image of drusen revealed the 'cap' sign (arrow), an empty space lined by high reflectivity signal (D). NFL: Nerve fibre layer, RPE: Retinal pigment epithelium.