Table 4.
Integrin expression and overall survival
| Integrin | Median OS (95% CI) in months | ||
|---|---|---|---|
| Low expression* | High expression | P | |
| Alpha1 | 39.3 (0.0-97.4) | 23.2 (0.0-46.8) | Ns |
| Alpha2 | 31.9 (0.0-81.1) | 18.4 (0.0-46.4) | Ns |
| Alpha3 | 61.8 (21.1-102.5) | 16.2 (12.2-20.2) | 0.012 |
| Alpha4 | 17.5 (0.0-50.5) | 30.6 (10.1-51.2) | Ns |
| Alpha5 | 44.4 (12.1-76.6) | 14.7 (9.0-20.4) | 0.006 |
| Alpha6 | 31.9 (15.0-48.8) | 36.1 (0.0-73.6) | Ns |
| Alpha7 | 31.9 (0.0-63.8) | 23.2 (0.0-52.2) | Ns |
| Alpha11 | 31.9 (10.0-53.8) | 32.8 (0.0-71.5) | Ns |
| AlphaV | 23.2 (0.0-56.1) | 30.6 (8.7-52.5) | Ns |
| Beta1 | 61.8 (0.0-129.3) | 16.1 (13.2-19.0) | 0.002 |
| Beta3 | 61.8 (22.8-100.8) | 11.5 (5.4-17.6) | 0.013 |
| Beta4 | 36.1 (20.6-51.5) | 16.3 (14.1-18.5) | Ns |
| Beta5 | 24.0 (3.5-44.6) | 23.2 (0.0-50.8) | Ns |
| Beta6 | 32.8 (4.5-61.1) | 31.9 (0.0-64.5) | Ns |
| Beta8 | 23.2 (3.0-43.4) | 36.1 (1.2-71.0) | Ns |
*Low = below median, High = above median