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The effect of TMZ, Qct or combination treatment on total p53 and phospho-p53. Western blot analysis after treatment with vehicle (DMSO), TMZ 400 μM for 48 hrs followed by Qct 75 μM for 24 hrs. A) DB-1 or B) SK Mel 5 and C) SK Mel 28 cell lines. *indicates loading control for the different blots shown.
