Fig. 4.

Hematoxylin and eosin as well as macrophage staining of cryosections of aortic lesions. Representative staining of aortic sinus plaques from uninfected C57BL/6 mice (a and e), P. gingivalis-infected C57BL/6 (b and f), uninfected TLR2^−/− mice (c and g), and P. gingivalis-infected TLR2^−/− mice (d and h). Sections were stained with hematoxylin and eosin (a–d), macrophage marker F4/80 (e–h) and isotype control (i). Arrows point to the luminal and adventitial surfaces of the aorta (a–d). Scale bars = 200 μm.