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. Author manuscript; available in PMC: 2011 Jul 1.
Published in final edited form as: Toxicol Appl Pharmacol. 2010 Apr 18;246(1-2):74–82. doi: 10.1016/j.taap.2010.04.009

Figure 4.

Figure 4

Expression of VCAM-1 in PECs lacking caveolin-1 (Cav-1). PECs treated with Cav-1 siRNA or control siRNA were exposed to PCB77 or PCB126 at 2.5 µM for 16 h. VCAM-1 protein levels in control siRNA (A) and Cav-1 siRNA (B) were observed using Western blot analysis. Densitometry results were normalized to β-actin, and represent the mean ± SEM, with n=3. Experiments were repeated a minimum of three times. The Western blot picture shown is a representative of three independent blots. (C) Monocyte adhesion to control and Cav-1 siRNA tansfected PECs were exposed to PCB126 (2.5 µM, 16 h) and TNF-α (4 ng/ml, 16 h). *Significantly different compared to DMSO control. #Significantly different compared to corresponding control siRNA group.