Figure 1.

FAK/Src complex mediated signaling pathway.

Notes: The FAK/Src complex transduces signals from a variety of membrane receptors such as tyrosine kinase repectors and integrins through the activation of intracellular signaling pathways such as PI3K-AKt and Ras-MAPK to reach a cellular response.

Abbreviations: ERK, extracellular signal regulated kinase; FA, focal adhesions; MEK, mitogen-activated protein; FAK, focal adhesion kinase; VEGF, vascular endothelial growth factor; MMPs, matrix metalloproteinases.