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. 2010 Jun 24;3:83–97. doi: 10.2147/ott.s6909

Figure 3.

Figure 3

Role of the FAK-Src complex in the malignant progression of solid tumors.

Notes: FAK and Src play a critical role in solid tumor progression mainly through its ability to promote the epithelial-mesenchymal transition associated with the metastatic behavior of solid tumors.

Abbreviations: ECM, extracellular matrix; EMT, epithelial mesenchynal transitions; FAK, focal adhesion kinase; Src, steroid receptor coactivator.