Figure 7. IL-1β inhibits parietal cell specific Shh expression.
Primary cultures of canine parietal cells were treated with PBS, IFNγ and IL-1β. Whole cell lysates were analyzed by immunoblot (A). Primary cultures of canine mucous cells were treated with PBS and IL-1β. Whole cell lysates were analyzed by immunoblot (B). Shown is the mean ± SEM for three separate parietal cell and mucous cell preparations. *P< 0.05 compared with PBS treatment. NS, not statistically significant.