Figure 8. IL-1β inhibits acid-dependent release of intracellular calcium.
Primary cultures of canine parietal cells pre-loaded with the Fura 2-AM dye were perfused with A) HBSS at pH 7 (upper panel), pH 5 (middle panel), or pH 5 with IL-1β (lower panel). B) Shown is a representative measurement of calcium binding to Fura 2 performed three times.