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. 2010 Jun 14;7:9. doi: 10.4103/1742-6413.64385

Figure 1.

Figure 1

Signet-ring adenocarcinoma in EBUS FNA and diagnostic pitfall. a, b) An EBUS FNA of demonstrates loosely cohesive tumor cells with relatively homogeneous nuclei, variable amounts of glassy cytoplasm, and some plasmacytoid cells (a. DQ stain, ×400; B. DQ stain, ×600). Occasional cells have marked nuclear enlargement, prominent nucleoli, and cytoplasmic vacuolization (b inset. DQ stain, ×600). c) Cell block from signet-ring adenocarcinoma (HandE stain, ×400). d) Goblet cell metaplasia from bronchial contamination (Pap stain, ×600) can mimic signet-ring adenocarcinomas.