Table 2.

Differential diagnosis based on background material

Necrotic background	Mucinous background	Tigroid background	Lymphoid background
Necrotizing granulomas	Nondiagnostic with mucin contamination	Germ cell tumor/Seminoma	Adequate, Negative for malignant cells with lymph node sampling
High grade tumor with necrosis	Negative for malignant cells with mucin contamination (lymphocytes present)	Glycogenated neoplasm (Squamous cell carcinoma, Ewing’s Sarcoma, clear cell tumors, others)	Lymphoma
	Mucinous adenocarcinoma		Mimics seen with small round blue cell tumors (example: necrotic/apoptotic background of small cell carcinoma)
	Mucinous Cystic Neoplasms [33] Malignant neoplasm with mucin contamination