Table 5.
Logistic regression for osteoporosis treatment—patients with low BMD or ICD-9 code
| Number of days from index date for treatment definition | ||||||
|---|---|---|---|---|---|---|
| 90 days | 180 days | 365 days | ||||
| Odds ratio | P value | Odds ratio | P value | Odds ratio | P value | |
| Age | ||||||
| 50–64 (ref) | ||||||
| 65–74 | 1.176 | <0.001 | 1.197 | <0.001 | 1.248 | <0.001 |
| 75+ | 1.565 | <0.001 | 1.524 | <0.001 | 1.514 | <0.001 |
| Race | ||||||
| White (ref) | ||||||
| Other | 1.369 | 0.059 | 1.289 | 0.127 | 1.197 | 0.281 |
| BMD T-score category | ||||||
| ≤−2.5 | 1.322 | 0.002 | 1.533 | <0.001 | 1.651 | <0.001 |
| >−2.5 (ref) | ||||||
| Unknown | 0.579 | <0.001 | 0.591 | <0.001 | 0.618 | <0.001 |
| Smoking | ||||||
| Current smoker (ref) | ||||||
| Former smoker | 0.758 | <0.001 | 0.754 | <0.001 | 0.761 | <0.001 |
| Never smoker | 0.715 | <0.001 | 0.715 | <0.001 | 0.711 | <0.001 |
| Unknown | 0.336 | <0.001 | 0.345 | <0.001 | 0.356 | <0.001 |
| Baseline BMI | ||||||
| Under/normal weight (ref) | ||||||
| Over weight | 0.805 | <0.001 | 0.779 | <0.001 | 0.739 | <0.001 |
| Obese | 0.538 | <0.001 | 0.513 | <0.001 | 0.473 | <0.001 |
| Very obese | 0.462 | <0.001 | 0.394 | <0.001 | 0.357 | <0.001 |
| Missing | 0.726 | <0.001 | 0.710 | <0.001 | 0.701 | <0.001 |
| Charlson Comorbidity Index | 0.955 | <0.001 | 0.963 | <0.001 | 0.968 | <0.001 |
| Oral corticosteroid | 1.338 | <0.001 | 1.336 | <0.001 | 1.309 | <0.001 |
| Rheumatoid arthritis | 1.395 | <0.001 | 1.512 | <0.001 | 1.732 | <0.001 |
BMI body mass index, BMD bone mineral density, ICD-9 International Classification of Diseases 9