Table 2.

Representative components and products synthesized using Bohdan MiniBlock platform

entry	R1	R2NH2	R3	yield (%)	purity (%)	product
1	S1	A10	M1	92	98	57
2	S1	A11	M4	12	98	58
3	S1	A12	M3	44	100	59
4	S1	A13	M4	6	100	60
5	S1	A14	M2	56	100	61
6	S1	A15	M2	68	100	62
7	S2	A10	M1	93	99	63
8	S2	A10	M4	82	99	64
9	S2	A11	M3	16	100	65
10	S2	A12	M1	84	90	66
11	S2	A12	M3	16	97	67
12	S2	A15	M2	82	100	68
13	S3	A10	M1	40	100	69
14	S3	A10	M3	32	95	70
15	S3	A10	M4	52	100	71
16	S3	A11	M3	18	91	72
17	S3	A12	M1	36	92	73
18	S3	A12	M4	20	100	74
19	S3	A13	M1	30	100	75
20	S3	A13	M3	34	93	76
21	S3	A13	M4	16	100	77
22	S4	A10	M1	32	100	78
23	S4	A11	M1	30	99	79
24	S4	A11	M3	24	97	80
22	S4	A12	M3	8	100	81
23	S4	A13	M1	22	100	82
24	S4	A13	M4	16	100	83

^a Reaction conditions: 1 (0.136 mmol), Pd₂(dba)₃.CHCl₃ (2 mol %), Michael acceptor (0.40 mmol), Bu₄NCl (0.136 mmol) in DMF at 110 °C for 14 h. ^b Purified by an automated preparative reverse phase HPLC (detected by mass spectroscopy). ^c Purity was determined by HPLC with peak area (UV) at 214 nm.