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. 2010 May 11;38(Web Server issue):W233–W238. doi: 10.1093/nar/gkq374

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© The Author(s) 2010. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — Recovery test for: (A) the C-MYC seed and (B) a random seed. Seeds of 51 known C-MYC targets or 51 random genes were submitted to Targetfinder.org. Then, repeatedly 10% of seed genes were randomly taken out and their similarity to the remaining genes was calculated. For consistent seeds, such as C-MYC, we observe a strong enrichment of top ranks (first bin of the histogram strongly enriched P < 10^{- 10}. For random seeds the histogram shows no significant enrichment of the top ranks .

Inline graphic — Recovery test for: (A) the C-MYC seed and (B) a random seed. Seeds of 51 known C-MYC targets or 51 random genes were submitted to Targetfinder.org. Then, repeatedly 10% of seed genes were randomly taken out and their similarity to the remaining genes was calculated. For consistent seeds, such as C-MYC, we observe a strong enrichment of top ranks (first bin of the histogram strongly enriched P < 10^{- 10}. For random seeds the histogram shows no significant enrichment of the top ranks .