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. 2010 May 21;38(Web Server issue):W109–W117. doi: 10.1093/nar/gkq424

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© The Author(s) 2010. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — SPEED analysis of downregulated genes in high-risk AML patients with CEBPa mutations. Screenshot of SPEED results shows TNF-α as the top-ranking upstream signaling pathway for target genes downregulated in high-risk AML patients with CEBPa mutations versus CEBPa wild-type. The pathways are sorted by FDR and graphical outputs aid in interpretation of the results.