Table 1.
Physiological variables
| MABP (mmHg) |
pH | pO2 (mmHg) |
pCO2 (mmHg) |
Hct (%) |
Glucose (mg/dl) |
|
|---|---|---|---|---|---|---|
| Experiment Set 1 | ||||||
| ICH + Vehicle | 93.9±15.3 | 7.40±0.05 | 80.4±3.9 | 41.9±3.8 | 46.0±5.7 | 100.8±10.6 |
| ICH + DFX 50 mg/kg 2h-delay | 101.2±10.8 | 7.40±0.05 | 81.0±3.5 | 43.0±3.0 | 47.6±5.5 | 110.1±15.3 |
| ICH + DFX 50 mg/kg 4h-delay | 87.7±17.0 | 7.38±0.08 | 80.5±6.6 | 44.7±5.2 | 42.0±6.1 | 99.0±13.5 |
| ICH + DFX 50 mg/kg 12h-delay | 96.4±15.2 | 7.38±0.07 | 78.8±6.1 | 43.3±4.6 | 45.4±3.8 | 112.6±15.2 |
| ICH + DFX 50 mg/kg 18h-delay | 102.4±9.8 | 7.41±0.09 | 81.4±5.0 | 42.9±4.0 | 42.2±4.9 | 107.4±17.0 |
| Experiment Set 2 | ||||||
| ICH + Vehicle | 89.9±12.5 | 7.41±0.05 | 81.4±4.9 | 42.0±3.9 | 45.2±5.0 | 110.8±10.1 |
| ICH + DFX 50 mg/kg for 2 d | 98.3±13.3 | 7.41±0.08 | 79.5±6.5 | 42.8±6.0 | 43.3±6.1 | 113.4±12.2 |
| ICH + DFX 50 mg/kg for 5 d | 101.7±12.9 | 7.40±0.08 | 80.9±5.8 | 41.5±5.6 | 42.1±6.3 | 109.0±8.5 |
| ICH + DFX 50 mg/kg for 7 d | 106.4±8.2 | 7.38±0.10 | 80.8±4.3 | 41.4±4.8 | 43.8±5.2 | 112.4±12.2 |
| ICH + DFX 50 mg/kg for 14 d | 102.2±10.8 | 7.39±0.07 | 81.4±6.1 | 44.8±5.1 | 41.2±5.9 | 110.9±14.7 |
| Sham + Vehicle for 14 d | 99.7±12.4 | 7.41±0.05 | 80.9±4.7 | 41.4±4.4 | 43.9±4.2 | 109.2±7.5 |
| Sham + DFX 50 mg/kg for 14 d | 99.6±10.0 | 7.42±0.08 | 81.6±3.5 | 42.6±3.1 | 45.5±3.8 | 110.4±9.2 |
| Experiment Set 3 | ||||||
| ICH + Vehicle | 101.0±8.8 | 7.40±0.07 | 82.0±6.0 | 41.1±2.8 | 45.1±6.8 | 101.4±12.3 |
| ICH + DFX 50 mg/kg 2h-delay | 103.4±12.0 | 7.42±0.10 | 81.4±5.5 | 43.8±5.2 | 41.8±6.0 | 111.2±8.4 |
| ICH + DFX 50 mg/kg 4h-delay | 107.6±9.0 | 7.40±0.03 | 79.9±6.0 | 41.6±4.5 | 44.6±4.4 | 103.0±10.5 |
| ICH + DFX 50 mg/kg 12h-delay | 96.4±15.6 | 7.41±0.05 | 79.1±7.1 | 42.3±7.6 | 44.1±3.0 | 112.2±9.2 |
| ICH + DFX 50 mg/kg 24h-delay | 99.4±14.8 | 7.41±0.06 | 81.4±3.6 | 41.1±4.5 | 44.1±5.1 | 98.4±17.7 |
| ICH + DFX 50 mg/kg 48h-delay | 100.8±11.5 | 7.42±0.08 | 80.8±4.9 | 41.0±3.0 | 42.2±5.2 | 100.2±11.5 |
Values are expressed as the means ± SD.