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Mean distance traveled scores (+SEM) of preweanling rats (n = 8 per group) given a challenge injection of cocaine (20 mg/kg, ip) prior to placement in activity chambers on PD 20. Rats were pretreated with cocaine (0–40 mg/kg, ip) while being maintained in the home cage on PD 19. The inset shows mean distance traveled collapsed across time blocks 1–12. *Significantly different from the 0 mg/kg group (p < .05).
