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. Author manuscript; available in PMC: 2011 Jun 1.
Published in final edited form as: Exp Clin Psychopharmacol. 2010 Jun;18(3):284–295. doi: 10.1037/a0019142

Figure 5.

Figure 5

Mean distance traveled scores (+SEM) of preweanling rats (n = 8 per group) given a challenge injection of cocaine (20 mg/kg, ip) prior to placement in activity chambers on PD 20. Rats had been pretreated with saline, MK-801 (0.3 mg/kg, ip), U50,488 (5 mg/kg, ip), methylphenidate (10 mg/kg, ip), or cocaine (30 mg/kg, ip) before being placed in activity chambers or anesthesia chambers on PD 19. The inset shows mean distance traveled collapsed across time blocks 1–12. *Significantly different from the saline group from the same chamber (p < .05). †Significantly different from the methylphenidate group from the anesthesia chamber (p < .05).