. Author manuscript; available in PMC: 2010 Sep 1.

Published in final edited form as: Arch Neurol. 2009 Sep;66(9):1120–1126. doi: 10.1001/archneurol.2009.196

Table 4. Cox models predicting occurrence of individual EPS and any EPS overall.

Parameter	Speech/facial expression	Tremor	Rigidity	Posture/Gait	Bradykinesia	Any EPS
Females	0.80 (0.43-1.51)	1.42 (0.52-3.83)	0.88 (0.48-1.59)	0.65 (0.39-1.08)	0.57 (0.30-1.09)	0.82 (0.56-1.19)
Age	1.01 (0.97-1.05)	1.05 (0.97-1.12)	1.04^* (1.01-1.08)	1.06^* (1.03-1.09)	1.05^* (1.01-1.09)	1.05^* (1.03-1.08)
Education	1.04 (0.92-1.12)	0.96 (0.84-1.09)	1.10^* (1.03-1.18)	1.07^* (1.01-1.13)	1.07 (0.40-1.05)	1.05^* (1.0161.10)
Cs	0.57^* (0.34-0.96)	0.947 (0.36-2.47)	0.37^* (0.23-0.59)	0.64^* (0.44-0.94)	0.65 (0.40-1.05)	0.58^* (0.43-0.78)

Risk ratios (95%CI) are tabulated.

Significant (95% CI not including 1) association.

EPS: extrapyramidal signs; Cs: Composite cognitive score