Skip to main content
. Author manuscript; available in PMC: 2010 Jul 2.
Published in final edited form as: Brain Res. 2004 May 8;1007(1-2):124–131. doi: 10.1016/j.brainres.2004.01.077

Fig. 1.

Fig. 1

Effects of METH and WIN-51,708 (WIN) on TH immunoreactivity in the striatum. Administration of 10 mg/kg METH resulted in a decrease in the intensity of TH immunoreactivity in four out of five animals 3 days after treatment. Pretreatment with 10 mg/kg WIN-51,708 prevented the METH-induced depletion of TH staining. Note that METH induces greater deficits of TH in the lCPu relative to the mCPu. Scale bar, 100 μm. CPu, caudate-putamen; lCPu and mCPu refer to lateral and medial aspects of the caudate-putamen, respectively; Cx, cortex.