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. 2010 May 5;30(18):6236–6246. doi: 10.1523/JNEUROSCI.0567-10.2010

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Copyright © 2010 the authors 0270-6474/10/306236-11$15.00/0

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Figure 5. — Behavioral deficits in MBP-hαsyn Tg mice are attenuated by GDNF infusion. To assess the behavioral effects of GDNF infusion, motor behavior was assessed via the pole test; total time taken to descend the pole (A) and time taken to face downward on the pole (B) were recorded. Olfactory function was assessed using the buried pellet test, and time taken to find the pellet was recorded (C) (n = 6; age, 8 months in each group). *Significant difference between saline-infused NTg and MBP-hαsyn Tg mice (p < 0.05, one-way ANOVA and post hoc Fisher). ^#Significant difference between saline-infused and GDNF-infused MBP-hαsyn Tg mice (p < 0.05, one-way ANOVA and post hoc Fisher). Error bars indicate SEM.