Table 1.
Clinical and demographic characteristic |
No lipid-lowering medication (n = 325) |
Lipid-lowering medication (n = 173) |
p value |
---|---|---|---|
Age years | 55 ± 11a | 62 ± 11 | 0.0001 |
Race, % black | 16 | 19 | 0.39 |
Education, % high school or more | 44 | 40 | 0.38 |
Total cholesterol, mg/dL | 200 ± 43 | 184 ± 40 | 0.0001 |
HDL-C, mg/dL | 55 ± 13 | 53 ± 12 | 0.15 |
LDL-C, mg/dL | 117 ± 38 | 99 ± 35 | 0.0001 |
Triglycerides, mg/dL | 152 ± 128 | 168 ± 114 | 0.05 |
Body mass index | 29 ± 6 | 30 ± 7 | 0.72 |
Waist/hip ratio | 0.83 ± 0.09 | 0.85 ± 0.10 | 0.18 |
History of hypertension, % | 53 | 67 | 0.002 |
History of dyslipidemia, % | 34 | 94 | 0.001 |
History of diabetes, % | 15 | 38 | 0.001 |
Current smoking, % | 18 | 19 | 0.78 |
Postmenopausal, % | 66 | 85 | 0.001 |
Current HRT, % | 55 | 43 | 0.03 |
Use of anxiolytics, % | 20 | 44 | 0.30 |
Use of antidepressants, % | 18 | 19 | 0.80 |
Significant disease defined as ≥ 50% stenosis in one or more epicardial arteries, % |
22 | 53 | 0.001 |
Mean ± standard deviation unless noted otherwise.