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. Author manuscript; available in PMC: 2011 Jun 23.
Published in final edited form as: Vaccine. 2010 May 14;28(29):4653–4660. doi: 10.1016/j.vaccine.2010.04.069

TABLE 1.

Data Inputs for Model Variables

Description (units) Mean Range Source
Lower Limit Upper Limit
COSTS ($US)
Procedures:
 Blood Culture 14.41 9.51 19.31 Hospitals
 Complete Blood Count 12.24 8.08 16.40 Hospitals
 Chest Radiograph 42.36 27.96 56.76 [41]
 C-Reactive Protein 74.00 48.84 99.16 Hospitals
 Computed Tomography 362.98 239.57 486.39 [41]
 Echocardiogram 295.28 194.88 395.68 [41]
 Erythrocyte Sedimentation Rate 4.93 3.25 6.61 Hospitals
 Incision and Drainage 451.29 297.85 604.73 [41]
 Lumbar Puncture 142.59 94.11 191.07 [41]
 Lumbar Puncture Tests 50.06 33.04 67.08 Hospitals
 Magnetic Resonance Imaging 359.06 236.98 481.14 [41]
 Nuclear Scan 298.14 196.77 399.51 [41]
 Triple Scan 269.86 178.11 361.61 [41]
 Urinalysis 14.41 9.51 19.31 Hospitals
 Urine Culture 14.47 9.55 19.39 Hospitals
 Vancomycin Level 47.71 31.49 63.93 Hospitals
 Voiding Cystourogram 275.87 182.07 369.67 [41]
 Plain Radiograph for Osteomyelitis 28.04 18.51 37.57 [41]
Side Effects from Vaccination
 Major Side Effects, Societal Perspective 667363 578778 755947 [42]
 Minor Side Effects 0.76 0.68 3.62 [43]
Hospitalization for:
 Bacteremia 7258.06 5302.62 9213.49 [44]
 Endocarditis 46521.69 33988.00 59055.38 [44]
 Osteomyelitis 15572.98 11377.37 19768.59 [44]
 Pneumonia 3617.27 2642.72 4591.83 [44]
 Soft Tissue Infection 4070.58 2973.90 5167.26 [44]
 Urinary Tract Infection 6292.67 4597.32 7988.01 [44]
PROBABILITIES (%)
Given S. aureus Infection
 Bacteremia 24.00 19.72* [45-50]
 Endocarditis 4.48 2.71* [7, 47]
 Pneumonia 33.33 14.06* [7, 45, 48-50]
 Urinary Tract Infection 2.40 2.27* [46, 50]
 Soft Tissue Infection 42.39 22.65* [7, 45-47]
 Mortality 23.26 9.87* [47, 51]
Given MRSA Infection:
 Bacteremia 27.64 25.88* [20, 52-56]
 Endocarditis 1.54 0.52* [57]
 Osteomyelitis 3.33 1.13* [20]
 Pneumonia 16.67 12.82* [20, 52, 57]
 Urinary Tract Infection 18.50 9.19* [55, 58]
 Soft Tissue Infection 24.37 26.14* [52, 54, 57, 59-61]
 Mortality 0.1935 0.12* [20, 51, 54, 57]
*

Standard Deviation