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SSBP2 and PML colocalize in PML-NBs in response to DNA damage in HEK293 cells. Cells were treated with 1uM etoposide (A) or 0.2 uM hydroxy urea (B) for 24 hours and stained with antibodies to SSBP2 [7] and PML (red). Merged images are shown on the far right. Note the colocalization of SSBP2 and PML only in the PML-NBs in response to DNA damage.
