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. 2010 Jul 2;5(7):e11431. doi: 10.1371/journal.pone.0011431

Table 3. Adjusted loss of FVC and FEV1 from year 5 to year 20 across race-sex specific quartiles of year 7 fibrinogen and CRP as well as linear regression coefficients for fibrinogen and log-transformed CRP as continuous variables.* .

Loss of Lung Function Fibrinogen Quartile (Year 7)
(Year 5 minus Year 20) 1 2 3 4 Beta P
FEV1 (mL) 446 456 464 487 0.333 <0.001
FVC (mL) 398 14 441 439 0.418 <0.001

*Adjusted for center, race-sex group, age, age-squared, height, and height-squared at year 20 [19], BMI at the time of fibrinogen or CRP measurement, change in waist circumference from year 7 to year 20, cumulative pack-years of cigarette smoking, and year 5 lung function.

Multivariable linear regression coefficient for the prediction of change in lung function from year 5 to year 20 by year 7 fibrinogen or CRP