Table 1. Baseline characteristics in patients with different β1AR variants.
All patients with AF N = 87 | Arg389Arg N = 36 | Arg389Gly N = 44 | Gly389Gly N = 7 | Ser49Ser N = 59 | Ser49Gly N = 28 | |
Women/Men (%) | 25/62 (29/71) | 8/28 (22/78) | 14/30 (31/69) | 3/4 (43/57) | 18/41 (31/29) | 7/21 (25/75) |
Age | 67.8±1.3 | 67.1±2.1 | 67.7±1.8 | 72.0±2.6 | 67.1±2.1 | 69.3±3.8 |
BMI | 26.6±0.4 | 27.2±0.5 | 26.4±0.5 | 24.8±1.0 | 26.4±0.7 | 27.0±0.5 |
Heart rate per minute | 106.6±1.7 | 110.7±2.7* | 104.8±2.4 | 96.9±5.8 | 107.4±1.8 | 104.9±2.4 |
PROCAM-Score | 44.4±0.5 | 44.2±0.7 | 44.9±0.8 | 42.8±1.3 | 44.4±0.7 | 44.4±0.5 |
Hypertension (%) | 47 (54) | 17 (47) | 25 (57) | 5 (71) | 33 (56) | 14 (50) |
CAD (%) | 32 (37) | 13 (36) | 18 (41) | 1 (14) | 22 (37) | 10 (36) |
Myocardial infarction (%) | 17 (20) | 9 (25) | 8 (18) | 0 (0) | 13 (22) | 4 (14) |
LVEF <40% | 22 (25) | 10 (28) | 11 (25) | 1 (14) | 16 (27) | 6 (21) |
CABG (%) | 7 (8) | 4 (11) | 3 (7) | 0 (0) | 5 (8) | 2 (7) |
Serum sodium (mmol/l) | 137.8±0.5 | 137.1±0.9 | 138.6±0.5 | 136.5±1.0 | 138.1±0.4 | 137.3±0.5 |
Serum potassium (mmol/I) | 4.1±0.1 | 4.1±0.1 | 4.1±0.1 | 4.3±0.3 | 4.0±0.1 | 4.3±0.4 |
BMI indicates body mass index, CAD indicates coronary artery disease, LVEF indicates left ventricular ejection fraction, CABG indicates coronary artery bypass grafting.
*p<0.05 vs. other variants.