. Author manuscript; available in PMC: 2011 Jun 1.

Published in final edited form as: Cancer Prev Res (Phila). 2010 Jun 1;3(6):707–717. doi: 10.1158/1940-6207.CAPR-09-0162

TABLE 1.

Genes differentially expressed following 3, 8 and 20 weeks of smoke exposure^a

Group A				Group G

Gene Symbol	3 weeks	8 weeks	20 weeks	Gene Symbol	20 weeks

Cyp1b1	11.38	8.19	9.81	Scel	2.06
Cry1	2.66	2.04	2.18	Igh-6	2.01
Cbr3	2.53	2.58	2.02	Acsl1	1.90
Ugt1a6a	2.52	1.67	1.73	Adprhl2	1.85
AU018778	1.88	1.63	2.02	Nr1d2	1.83
EG245174	1.85	1.90	1.58	Mylpf	1.81
Ces3	1.80	1.74	1.64	Cxcl1	1.80
Tef	1.79	1.79	1.38	Gclc	1.78
Hdc	0.52	0.52	0.55	Gpx2	1.72
Col3a1	0.42	0.41	0.49	LOC100039206	1.66
				4922501L14Rik	1.61
Group B				Slc40a1	1.58

Gene Symbol	3 weeks	8 weeks	20 weeks	Fbln2	1.53

Ier3	2.00	1.86	-	Gmnn	1.50
Ttc21a	0.54	0.50	-	Fabp3	1.48
				Bclaf1	1.48
Group C				Tsix	1.46

Gene Symbol	3 weeks	8 weeks	20 weeks	Cldn12	1.45

Akr1c14	2.60	-	3.02	Tex12	1.44
Pdia6	0.64	-	0.60	Cox7a2	1.42
Igfbp3	0.47	-	0.54	Slc39a4	1.41
				Bmp1	1.41
Group D				Pigc	1.41

Gene Symbol	3 weeks	8 weeks	20 weeks	Ak3l1	1.41

Fkbp5	-	2.36	2.35	Gas1	1.40
Gsta4	-	2.02	1.81	1700020C11Rik	1.40
Hsp90aa1	-	0.58	0.68	Elof1	1.40
Ncald	-	0.54	0.71	LOC100043812	1.39
				Ndufc1	1.39
Group E		Group F		Gsto1	1.38

Gene Symbol	3 weeks	Symbol	8 weeks	Cabc1	1.38

Dnajb7	2.32	Gc	2.53	Prl3d1	1.38
Wipf3	1.98	Serpina1e	2.28	Hnrnpu	1.37
Ppap2b	1.84	Tdrd5	1.78	Fancm	1.37
Gstm1	1.64	Ephx1	1.76	Zfp11	1.37
Lonrf3	1.64	Tdrd7	1.57	Apbb2	1.35
Tspan15	0.63	Apol6	1.56	Snx14	1.34
Igf1	0.62	Slco4c1	0.61	Akr1c19	1.34
Col1a2	0.60	Dach1	0.53	Tmem57	1.33
Cd34	0.58	Mat2a	0.52	Esd	1.32
Arhgap28	0.58	Axud1	0.52	Josd3	1.32
Plekha6	0.58	Errfi1	0.50	Sorbs1	1.31
Fbp2	0.56	Pitpnb	0.38	Appl2	1.31
Npr3	0.53			D19Ertd652e	1.30
Igsf10	0.52			Xdh	1.30
D0H4S114	0.47			Vdac1	1.30
Slc38a5	0.45			Lias	1.29
Npnt	0.40			RP23-292J1.1	1.27
				Bcnp1	1.27
				1600020E01Rik	1.27
				Tnk2	1.27
				Trhde	1.26
				Gtf2a2	1.25
				Trub2	1.25
				Bach1	1.25
				Nfatc4	1.24
				Zfp612	1.24
				Krtap16-10	1.24
				Khdc1a	1.23
				Ncdn	1.22
				Ptp4a1	1.21
				Pygb	0.84
				Cyhr1	0.84
				Ptpn6	0.83
				Maged2	0.83
				Col4a1	0.83
				Abca3	0.82
				Slc15a4	0.82
				Ankrd17	0.81
				Itgb7	0.81
				Ubr5	0.80
				Wdr79	0.79
				Srebf1	0.79
				Rhbdd3	0.79
				Stmn1	0.79
				Ubxd2	0.79
				Ptms	0.79
				Pdia5	0.78
				Azin1	0.78
				Zdhhc18	0.78
				Gm2a	0.76
				Bst2	0.75
				Rac2	0.75
				Selplg	0.75
				Diablo	0.74
				Dhrs3	0.74
				Tia1	0.73
				Mpv17	0.73
				Hba-a1	0.73
				Banp	0.73
				Phtf1	0.73
				Gcap14	0.72
				Cybb	0.72
				Stip1	0.72
				Laptm5	0.72
				Reps1	0.72
				Lmbr1	0.71
				Myo1e	0.71
				Arf1	0.71
				Bbx	0.71
				Cbx5	0.71
				Tbc1d15	0.71
				Sdc4	0.70
				Comtd1	0.70
				Xbp1	0.70
				Lpcat1	0.70
				Igtp	0.69
				Ywhaq	0.69
				9030425E11Rik	0.68
				Rnf113a1	0.68
				Hsp90ab1	0.67
				Tcfcp2l1	0.67
				Ipo5	0.66
				Ahcyl2	0.65
				Ndst1	0.65
				LOC100043546	0.65
				Aspm	0.64
				H2-K1	0.64
				Hbb-b1	0.64
				Thra	0.63
				2810025M15Rik	0.63
				Leo1	0.62
				5830443L24Rik	0.60
				Rlbp1l1	0.60
				Lrp2	0.58
				Spnb2	0.57
				Sparc	0.56
				Smc1b	0.54

Differentially expressed genes were identified using limma package with a P-value threshold of 0.001. Categorization of genes (Groups A-G) corresponds to the same classification in Figure 1A. Values represent the fold change in linear scale.