Skip to main content
. Author manuscript; available in PMC: 2011 Jan 1.
Published in final edited form as: Cancer Res. 2010 Jun 1;70(13):5618–5627. doi: 10.1158/0008-5472.CAN-09-3740

Figure 1.

Figure 1

Atoh1 accelerates MB formation and inhibits neuronal differentiation. (A) Survival curves of orthotopically transplanted mice that received GNPs from tumor-prone Ptch1+/−;Cdkn2c−/− animals (black) or those infected with vectors encoding Atoh1/RFP (red) or Gli1/GFP (green). (B) MBs accelerated by Gli1 (panels a–f) or Atoh1 (panels g–l) were visualized by H&E staining (panels a and g), by immunofluorescence for the neuronal markers indicated at the left of panels b–f and h–l,. Magnifications are indicated on the right side of the panels.