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. Author manuscript; available in PMC: 2011 Jul 1.
Published in final edited form as: Cancer Res. 2010 Jun 8;70(13):5486–5496. doi: 10.1158/0008-5472.CAN-10-0713

Fig 3.

Fig 3

Transient knockdown of Nrf2 expression by Nrf2-siRNA sensitized SPEC-2 cells to chemotherapeutic drugs. (A) The protein levels of Nrf2, NQO1, and γ-GCS were compared between Ishikawa and SPEC-2 cells transfected with Nrf2-siRNA or control siRNA. (B) Ishikawa and SPEC-2 cells were transfected with Nrf2-siRNA or control siRNA for 24 h, and then treated with different doses of cisplatin or paclitaxel for another 48 h. Cell viability was assessed by MTT assay. The data are presented as means ± SD, *P < 0.05.