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. 2010 Mar 1;38(12):3963–3974. doi: 10.1093/nar/gkq108

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© The Author(s) 2010. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 5. — Functional analysis of the dynamic localization of Ntg1. (A) The H₂O₂ sensitivity of wild type (WT), apn1 ntg2 ntg1 rad1 (BER⁻/NER⁻), apn1 ntg2 NTG1 rad1 (BER*_wt/NER⁻) and apn1 ntg2 ntg1_mutant rad1 (BER*_mutant/NER⁻) cells were assessed. The percent survival was set to 100% for untreated samples and was determined for 0, 2, 4 and 6 mM H₂O₂ doses. (B) The MMS sensitivity of wild type (WT), (BER⁻/NER⁻), (BER*_wt/NER⁻) and (BER*_mutant/NER⁻) cells were assessed. The percent survival was set to 100% for untreated samples and was determined for 0, 1, 3 and 5 mM MMS doses. Error bars indicate standard deviations in data.