Figure 2.
Length distributions of TNR types in the human genome and in exons. (A) For each type, the graph shows the number (y-axis) of TNRs of a given length (x-axis) identified in the human genome (color bars) and in exons (black bars). Bars indicated on the x-axis as >30 and 40 show the combined number of TNRs 31–40 and >40 U in length, respectively. An inset, shown in some graphs, was scaled up to emphasize the length distribution details specific for longer (less frequent) TNRs. (B) Heatmap graph showing the Kolmogorov–Smirnov statistic (D) for the pairwise length distribution comparisons of all TNR types. The color legend is shown next to the graph. The P-values for individual comparisons are also indicated on the graph (in each cell the value of the D statistic is given below). The P < 0.05 are indicated in red. The cluster of light blue squares represents groups of TNR types with similar length distributions. (C) Cumulative fraction plots comparing the TNR length distribution in exons (dashed line) and in non-exon sequences (genome sequence not covered by exons) (solid lines). The y-axis indicates the cumulative fraction of TNRs for certain TNR lengths (x-axis). The maximum distance between fraction plots (K–S-test, D statistic) and appropriate P-values are indicated on the plots.
