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. Author manuscript; available in PMC: 2011 Jan 1.
Published in final edited form as: Cancer Res. 2010 Jun 1;70(13):5549–5557. doi: 10.1158/0008-5472.CAN-09-4254

Figure 2. G12VKRAS induces pigmented epithelioid melanocytoma in mice.

Figure 2

A. Photograph showing an elevated dark lesion in the peri-orbital area of a TM-treated G12VKRAS;Tyr::CreERT2 mouse

B. Low power magnification of an H&E-stained paraffin section of a pigmented epithelioid melanocytoma from the peri-orbital area of a TM-treated G12VKRAS;Tyr::CreERT2 mouse. Note the absence of a junctional component.

C. High power magnification photomicrograph of the boxed area in B. Note the presence of heavily melanin-laden epithelioid cells (arrows) and less pigmented spindle cells (arrow heads).