Table 2.

Biomarkers for influenza vaccine toxicity.

Category	Accession No.	Symbol	Brief description
IFN inducible gene	NM_172019	IFI47	Mouse homolog may be a guanine nucleotide-binding protein induced by IFN-gamma
	AF329825	TRAFD1	Putative TRAF-interacting zinc finger protein
	NM_019242	IFRD1	May be involved in proliferation of neuronal and glial precursors
IFN inducible, immune response	NM_001033691	IRF7	Unknown
	NM_134350	MX2	Involved in inhibiting vesicular stomatitis virus
Immune response	NM_172222	C2	Likely component of the classical pathway of the complement cascade
	NM_012708	PSMB9	Subunit of the proteasome complex, which may play a role in protein catabolism
	NM_032056	TAP2	Transports peptides into the ER lumen for binding with MHC class I molecules; plays a role in antigen processing and presentation
	NM_033098	TAPBP	Facilitates the binding of MHC class I molecules to the transporter associated with antigen processing (TAP) in MHC class I assembly
	NM_017264	PSME1	May play a role in proteasome activation
Chemokine and Cytokine function	AF065438	LGALS3BP	Displays differential expression in a fibroblast cell line transformed by human T-cell leukemia virus type 1 Tax protein
	NM_012977	LGALS9	A highly selective urate transporter/channel
	NM_053819	TIMP1	Acts as an inhibitor of metalloprotease activity; may play a role in vascular tissue remodeling
	NM_023981	CSF1	Plays a role in macrophage formation
	NM_145672	CXCL9	Chemokine which plays a role in the recruitment of mononuclear cells and in allograft rejection
	XM_223236	CXCL11	Mouse homolog is a chemokine and is involved in the immune response
Transcription activity	AJ302054	ZBP1	DNA binding protein; thought to bind Z-DNA, which is largely controlled by the amount of supercoiling