Table 2.

Gene annotation enrichment among top predicted genes in the generic IFNG and the IFNG-vaccine networks.

Category	Term	Count	P-Value	FDR
GOTERM_BP_ALL	GO:0050896~response to stimulus	43	2.99E − 22	5.71E − 19
GOTERM_BP_ALL	GO:0007154~cell communication	39	5.74E − 13	1.10E − 09
GOTERM_BP_ALL	GO:0007165~signal transduction	35	9.70E − 11	1.86E − 07
GOTERM_BP_ALL	GO:0006950~response to stress	29	7.14E − 20	1.37E − 16
GOTERM_BP_ALL	GO:0030154~cell differentiation	28	6.94E − 13	1.33E − 09
GOTERM_BP_ALL	GO:0006952~defense response	26	7.12E − 23	1.36E − 19
GOTERM_BP_ALL	GO:0006955~immune response	26	8.88E − 18	1.70E − 14
GOTERM_BP_ALL	GO:0008283~cell proliferation	23	9.37E − 16	1.70E − 12
GOTERM_BP_ALL	GO:0008219~cell death	23	2.28E − 15	4.46E − 12
GOTERM_BP_ALL	GO:0006915~apoptosis	22	9.38E − 15	1.78E − 11
GOTERM_BP_ALL	GO:0007242~intracellular signaling cascade	19	4.85E − 07	9.27E − 04
GOTERM_BP_ALL	GO:0001775~cell activation	18	5.86E − 19	1.12E − 15
GOTERM_BP_ALL	GO:0006954~inflammatory response	17	8.26E − 16	1.49E − 12
GOTERM_BP_ALL	GO:0046649~lymphocyte activation	14	1.77E − 14	3.38E − 11
GOTERM_BP_ALL	GO:0006468~protein amino acid phosphorylation	14	2.60E − 07	4.98E − 04
GOTERM_BP_ALL	GO:0006807~nitrogen compound metabolic process	13	4.47E − 08	8.56E − 05
GOTERM_BP_ALL	GO:0042110~T cell activation	12	9.02E − 14	1.73E − 10
GOTERM_BP_ALL	GO:0048534~hemopoietic or lymphoid organ development	12	4.57E − 11	8.74E − 08
GOTERM_CC_ALL	GO:0005576~extracellular region	29	5.33E − 18	8.27E − 15
GOTERM_MF_ALL	GO:0005125~cytokine activity	19	5.30E − 21	9.51E − 18
GOTERM_MF_ALL	GO:0008083~growth factor activity	12	6.77E − 12	1.21E − 08
KEGG_PATHWAY	hsa04060:Cytokine-cytokine receptor interaction	23	7.90E − 16	9.77E − 13
KEGG_PATHWAY	hsa04620:Toll-like receptor signaling pathway	13	3.12E − 10	3.91E − 07
KEGG_PATHWAY	hsa04660:T cell receptor signaling pathway	12	2.04E − 09	2.57E − 06
KEGG_PATHWAY	hsa04630:Jak-STAT signaling pathway	11	2.99E − 06	0.003745