Fig. 5.

Immunohistochemical staining for olfactory marker protein (OMP) and green fluorescent protein (GFP). The staining was performed on the consecutive sections of the olfactory turbinates. OMP-positive cells were observed (A) in the olfactory neuroepithelium from the healthy wild-type mice that were not treated with 3-mehtylindole and that had normal olfactory function, while there were no GFP-positive cells (B). There were no OMP- (C) or GFP-positive cells (D) in the olfactory neuroepithelium from the anosmic mice that were not transplanted with neural stem cells. In the transplanted mice, the cells were only positive for OMP (E) but not for GFP (F) in some olfactory neuroepithelial regions, whereas cells that were positive for both OMP (G) and GFP (H) were observed in some regions.