Table 4.
Junction-Sequence Signatures
|
PARK2 (Germ Cell Lines) |
PARK2 (Cancer Cell Lines) |
DMD (Germ Cell Lines) |
DMD (Cancer Cell Lines) |
|||||
|---|---|---|---|---|---|---|---|---|
| N | % | N | % | N | % | N | % | |
|
Junctions with Extended Homologies | ||||||||
| Total | 7 | 4.3% | 1 | 3.1% | 2 | 1.0% | 0 | 0.0% |
| Junctions with Microhomologies (Identical Sequences ≤ 8 bp) | ||||||||
| ≥ 9 bp identical sequences | 0 | 0.0% | 0 | 0.0% | 0 | 0.0% | 0 | 0.0% |
| 8 bp identical sequences | 1 | 0.6% | 0 | 0.0% | 0 | 0.0% | 0 | 0.0% |
| 7 bp identical sequences | 1 | 0.6% | 1 | 3.1% | 1 | 0.5% | 0 | 0.0% |
| 6 bp identical sequences | 1 | 0.6% | 0 | 0.0% | 4 | 2.0% | 0 | 0.0% |
| 5 bp identical sequences | 8 | 4.9% | 1 | 3.1% | 6 | 3.0% | 1 | 16.7% |
| 4 bp identical sequences | 9 | 5.6% | 5 | 15.6% | 14 | 7.1% | 1 | 16.7% |
| 3 bp identical sequences | 23 | 14.2% | 4 | 12.5% | 33 | 16.8% | 0 | 0.0% |
| 2 bp identical sequences | 26 | 16.0% | 3 | 9.4% | 30 | 15.2% | 1 | 16.7% |
| 1 bp identical sequences | 28 | 17.3% | 5 | 15.6% | 40 | 20.3% | 0 | 0.0% |
| Total | 97 | 59.9% | 19 | 59.4% | 128 | 65.0% | 3 | 50.0% |
| Junctions without Extended Homologies or Microhomologies | ||||||||
| Insertions of repetitive sequences | 0 | 0.0% | 2 | 6.3% | 1 | 0.5% | 0 | 0.0% |
| Insertions of sequences of undetermined origin | 51 | 31.5% | 8 | 25.0% | 51 | 25.9% | 2 | 33.3% |
| No insertions | 7 | 4.3% | 2 | 6.3% | 15 | 7.6% | 1 | 16.7% |
| Total | 58 | 35.8% | 12 | 37.5% | 67 | 34.0% | 3 | 50.0% |