Array-CGH Profiles at 8q13
The 400K oligonucleotide arrays performed on patients from families 1, 2, 3, and 4 were analyzed with the Agilent scanner and the Feature Extraction software (v. 9.1.3). For each patient, positive and negative log2 ratio values are depicted by green and red vertical bars, respectively. Deleted segments are highlighted in gray whereas black vertical bars delimit the minimal deleted interval. RefSeq genes (including SULF1 and SLCO5A1) are indicated in blue. The black box at the bottom indicates the BAC probe RP11-676B14, which was used by FISH validation. Note that five noncoding RNA pseudogenes are predicted or present in the deleted regions.