Table 1.

Clinical Features of Subjects with Chromosome 17q23.2 Microduplication

Patient	5377-01	5377-02	5377-03	5377-06	5103-01	5103-03	5035-01	5035-04	5035-05
Age	3	5	35	D/C	10	44	54	47	47
Sex	M	F	M	M	M	M	M	M	M
Height	4%	10%	5%	10%	4%	10%	5%	50%	50%
Clubfoot	Bilateral Grade III	-	Bilateral Grade III	Bilateral (unknown grade)	Bilateral Grade IV	Right Grade IV	Bilateral (unknown grade)	Bilateral (unknown grade)	Bilateral (unknown grade)
Clubfoot treatment	Conservative	-	Conservative	Conservative	Surgery	Surgery	Surgery	Surgery	Surgery
Hip dysplasia	-	+	-	-	-	-	-	-	-
Nail hypoplasia	-	-	-	N/A	+	+	-	-	-
Radiographic Abnormalities of Pelvis
Acetabular dysplasia	+	+	-	N/A	-	+	N/A	N/A	N/A
Coxa valga	+	+	+	N/A	+	-	N/A	N/A	N/A
Genu valgum	+	-	-	N/A	-	-	N/A	N/A	N/A
Tall, narrow ilium	-	+	+	N/A	+	+	N/A	N/A	N/A
Thickened inferior pubic ramus (ischium)	+	+	+	N/A	+	+	N/A	N/A	N/A
Infra-acetabular axe-cut notches	+	-	+	N/A	-	+	N/A	N/A	N/A
Lack of normal iliac flare	+	+	+	N/A	+	+	N/A	N/A	N/A
Radiographic Abnormalities of Feet
Short and thickened first and/or second metatarsals	+	N/A	+	N/A	+	+	-	+	+
Short calcaneus	+	N/A	+	N/A	+	+	+	+	-
Hypoplastic distal tibial epiphysis	+	N/A	+	N/A	+	+	N/A	+	N/A
Tufted distal phalanx of the first toe	+	N/A	+	N/A	+	+	+	+	+

N/A indicates not available; D/C indicates deceased.