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. Author manuscript; available in PMC: 2011 May 12.
Published in final edited form as: Chem Rev. 2010 May 12;110(5):2795–2838. doi: 10.1021/cr900300p

Table 1.

Results of FGR versus white light resection for patients with malignant glioma in a multicenter randomized trial.78 Data adapted from Stummer et al. with permission from Elsevier.

FGR (n=139) White light (n=131) OR (95% CI) p

All patients 90 (65%) 47 (36%) 3·28 (1·99–5·40) <0·0001*
Age (years) ·· ·· 3·42 (2·06–5·70) <0·0001
·· ·· 0·679
≤55 35/45 (78%) 20/43 (47%) 4·03 (1·60–10·14) 0·0025*
>55 55/94 (59%) 27/88 (31%) 3·19 (1·73–5·87) 0·0002*

Karnofsky performance scale ·· ·· 3·27 (1·98–5·40) 0·0001
·· ·· ·· 0·369
70–80 13/28 (46%) 9/31 (29%) 2·12 (0·72–6·20) 0·1676*
>80 77/111 (69%) 38/100 (38%) 3·70 (2·09–6·54) <0·0001*

Tumour location ·· ·· 3·26 (1·97–5·40) <0·0001
·· ·· ·· 0·351
Non-eloquent 45/65 (69%) 26/55 (47%) 2·51 (1·19–5·30) 0·0148*
Eloquent 45/74 (61%) 21/76 (28%) 4·06 (2·05–8·07) <0·0001*