Table 3.

Association analysis between SNPs of FSIP1 gene and the fall of FEV₁ by aspirin provocation.

rs#	C/C		C/R		R/R		P*
	n	Fall rate	n	Fall rate	n	Fall rate
rs1602543	356	9.74 ± 13.12	205	8.25 ± 13.03	31	9.88 ± 15.55	0.43
rs7179742	300	8.29 ± 12.05	241	9.49 ± 14.15	51	13.54 ± 14.55	0.01
rs1021411	335	8.84 ± 12.89	223	9.58 ± 13.87	34	10.88 ± 12.14	0.26
rs1021410	299	8.30 ± 12.03	245	9.56 ± 14.13	48	13.38 ± 14.86	0.01
rs12440567	322	8.36 ± 12.33	227	9.81 ± 14.15	43	12.76 ± 14.11	0.02
rs2576932	157	11.33 ± 15.8	290	8.34 ± 11.80	144	8.76 ± 12.69	0.06
rs10520151	564	9.15 ± 13.02	27	0.71 ± 17.32	1	13.8	0.50
rs16969802	324	8.38 ± 12.32	225	9.80 ± 14.18	43	12.68 ± 14.14	0.02
rs12911842	341	9.57 ± 13.93	210	9.30 ± 12.54	41	6.09 ± 9.94	0.14
rs7179417	156	11.40 ± 15.8	291	8.25 ± 11.78	145	8.87 ± 12.64	0.06
rs4115216	155	11.46 ± 15.8	292	8.23 ± 11.77	145	8.87 ± 12.64	0.06
rs8033957	162	9.08 ± 13.21	284	8.22 ± 11.59	145	11.41 ± 15.8	0.10
rs6492915	162	9.08 ± 13.21	284	8.22 ± 11.59	145	11.41 ± 15.8	0.10
rs8031241	153	11.52 ± 15.9	291	8.20 ± 11.76	147	8.91 ± 12.62	0.06
rs1906164	339	9.25 ± 12.60	216	9.21 ± 13.94	37	9.24 ± 14.74	0.98

*P-values of regression analysis represent the co-dominant model controlling sex, smoking status, and atopy as covariates.

C/C, C/R and R/R indicate the homozygote of common allele, and the heterozygote and homozygote of rare allele, respectively.

Fall rate values are mean ± standard deviation.