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. Author manuscript; available in PMC: 2010 Jul 6.
Published in final edited form as: N Engl J Med. 2008 Sep 11;359(11):1108–1115. doi: 10.1056/NEJMoa0800777

Table 1.

Characteristics of the Study Sample.*

Characteristic Subjects
(N = 991)
Age — yr 62.3±8.6
Female sex — no. (%) 565 (57)
White race — no. (%) 922 (93)
Body-mass index 28.5±5.6
Current smoker — no./total no. (%) 106/946 (11)
Characteristics of the right knee — no./total no. (%)
    Any pain, aching, or stiffness in the previous month 278/965 (29)
    Pain, aching, or stiffness on most days 226/966 (23)
    Any episode of buckling in the previous 3 months 64/964 (7)
    Radiographic evidence of osteoarthritis§ 171/963 (18)
    Symptomatic osteoarthritis 90/942 (10)
    Previous injury 139/966 (14)
    Previous surgery 56/966 (6)
*

Plus–minus values are means ±SD.

Race was self-reported.

The body-mass index is the weight in kilograms divided by the square of the height in meters. Data for the body-mass index were missing for 13 subjects.

§

Tibiofemoral osteoarthritis was defined as a grade of 2 or higher on the Kellgren–Lawrence scale.

Symptomatic osteoarthritis was defined as knee pain, aching, or stiffness on most days and radiographic evidence of tibiofemoral osteoarthritis as defined by a grade of 2 or higher on the Kellgren–Lawrence scale.

Previous injury was defined as a knee injury leading to a reduced ability to walk for at least 3 days or the use of crutches or a cane.