Figure 5.

Association of FHIT gene promoter methylation and its protein expression with gender, age and tumor classification in DTC. FHIT gene promoter methylation and its protein expression in DTC of (A) male (n = 19) and female (n = 46), (B) the patients at < 45 years old (n = 30) and ≥ 45 years old (n = 35), and (C) FTC (n = 23) and PTC (n = 42) (C) were determined by PCR-based methylation analysis and IHC staining, respectively. There is no statistical significance between the groups. FTC: follicular thyroid carcinoma; PTC: papillary thyroid carcinoma.